Had to change some 700 lines of code in about 120 files - time to give that regular expressions manual another look.

The complete line of code looked like so:

I needed to get rid of the following javascript snippet that was not needed any longer:

onClick="open_win('16/johannes_kreuz.html',740,660,0,0,0,0,0,1,1,0,5,'win1');return false;" target="_blank"> 

above line(no line brakes) should change into

target="_blank">

Solution in Homesite 5.5:
Extended Replace, turn on Regluar Expressions,

Find what:
onClick=[\(A-Za-z0-9_/.,'\);" =]*>

Replace with:
target="_blank">

The operation about three seconds ;)

onClick=     is the first anchor

[\(A-Za-z0-9_/.,'\);" ]   encludes all characters found between the first anchor and the second anchor - which is

*>   where * is a special character: it matches the specified characters ">" throughout the entire document.

Helpful site:   Jim Montgomery's site - Thanks Jim!

http://jimmont.com/resrc/regex.htm 

and of course, the homesite help, now hosted by Adobe ;)

http://www.adobe.com/livedocs/coldfusion/5.0/Using_HomeSite/language5.htm